Melanoma is a malignant cutaneous neoplasm characterized by the uncontrolled proliferation of melanocytes. Importantly, melanoma does not exhibit distinct age, sex, or racial predilections, underscoring the need for diligence in the monitoring and early detection of suspicious lesions across all demographics. Dermoscopy, a non-invasive diagnostic technique that allows for enhanced visualization of pigmented skin lesions, plays a pivotal role in the early identification of melanoma. There are presented three cases of melanoma in situ in different groups of ages, emphasising the importance of detecting them in time, surgery excision and follow up. Collaboration of the dermatologist, oncologist and healthcare professionals is very important to defeat the diseases and to lower the morbidity of this malignancy.